Similar to naltrexone both in structure and in name, naloxone is another opioid antagonist that has a bit of a different role in treating heroin withdrawal and addiction recovery.
As mentioned earlier, heroin and other opioids interact with the brain and body by binding to and stimulating opioid receptors. And while the stimulation of these receptors can lead to euphoria, pain relief, and a physical “high” at certain levels, over stimulation can decrease respiration to dangerous levels and cause an overdose.
That’s where naloxone comes in. This opioid antagonist not only blocks other opioids from attaching to the receptor (like naltrexone), it also actually reverses the effects of opioid stimulation.
As such, it can effectively cure a heroin overdose and bring respiration back to normal, safe levels.
What’s more, naloxone has also been developed into an easily-administrable nasal spray form. This product, called Narcan, is cheap, simple-to-use, and incredibly effective.
And given that the only prior way to administer the drug beforehand was through injection (which required past medical experience to do), this development is a big one for the addiction community. Now anyone can save a life during an opioid overdose.
Narcan is so easy to use that it’s become a common first aid medication in offices, coffee shops, and colleges across the nation.
Due to the exceptionally high risk of relapse among heroin users, naloxone is a real life-saver.